Trypanosome pathogens of plants
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چکیده
منابع مشابه
A Receptor’s Tale: An Eon in the Life of a Trypanosome Receptor
African trypanosomes have complex life cycles comprising at least ten developmental forms, variously adapted to different niches in their tsetse fly vector and their mammalian hosts. Unlike many other protozoan pathogens, they are always extracellular and have evolved intricate surface coats that allow them to obtain nutrients while also protecting them from the immune defenses of either insect...
متن کاملExpression and antimicrobial activity analysis of dermaseptin B1 recombinant peptides in tobacco transgenic plants
Recently, new molecular breeding and genetic engineering approaches have emerged to overcome the limitations of conventional breeding methods in generating disease-resistance transgenic plants. The use of antimicrobial peptides (AMPs) to produce transgenic plants resistant to a wide range of plant pathogens has achieved great success. Among huge number of AMPs, Dermaseptin B1 (DrsB1), an antimi...
متن کاملWhite Paper: Pathogenomics of Trypanosomatid parasites - August 2007
The family Trypanosomatidae of the protistan order Kinetoplastida includes three major lineages of human pathogens – the Leishmania and the African and American trypanosomes – that each rank within the top 10 in terms of global impact. The combined impact measured by DALY of these three parasites approaches 5 million. There are currently five ‘completed’ genomes of kinetoplastids: one African t...
متن کاملDepletion of Trypanosome CTR9 Leads to Gene Expression Defects
The Paf complex of Opisthokonts and plants contains at least five subunits: Paf1, Cdc73, Rtf1, Ctr9, and Leo1. Mutations in, or loss of Paf complex subunits have been shown to cause defects in histone modification, mRNA polyadenylation, and transcription by RNA polymerase I and RNA polymerase II. We here investigated trypanosome CTR9, which is essential for trypanosome survival. The results of ...
متن کاملThe Fantastic Voyage of the Trypanosome: A Protean Micromachine Perfected during 500 Million Years of Engineering
The human body is constantly attacked by pathogens. Various lines of defence have evolved, among which the immune system is principal. In contrast to most pathogens, the African trypanosomes thrive freely in the blood circulation, where they escape immune destruction by antigenic variation and incessant motility. These unicellular parasites are flagellate microswimmers that also withstand the h...
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